NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(11) [November 2009] >


Title: Synthesis and biological activities of new 7-o--D-glucopyranosyloxy-3-(3-oxo-3-arylprop-1-enyl)-chromones
Authors: Hatzade, K M
Taile, V S
Gaidhane, P K
Umare, V D
Haldar, A G M
Ingle, V N
Keywords: Chromones
,-unsaturated carbonyl compounds
glucosylation
o--D-glucosides
biological activity
Issue Date: Nov-2009
Publisher: CSIR
Abstract: A convenient route to synthesize some new medicinally important 7-hydroxy-3-(3-oxo-3-arylprop-1-enyl)-chromones 2 is described by the interaction of 7-hydroxy-3-formyl chromone 1 with various substituted acetophenones which on condensation with 2,3,4,6-tetra-o-acetyl--D-glucopyranosyl bromide affords 2,3,4,6-tetra-o-acetyl--D-glucopyranosyloxy-3-(3-oxo-3-arylprop-1-enyl)-4H-chromen-4-ones 3. Later on deacetylation with anhydrous zinc acetate in methanol gives 7-o--D-glucopyranosyloxy-3-(3-oxo-3-arylprop-1-enyl)-4H-chromen-4-ones 4. These compounds are evaluated for their in vitro antimicrobial and antioxidant activity. The structures of these newly synthesized compounds are established by IR, NMR, mass spectra, elemental analysis and chemical analysis.
Page(s): 1548-1557
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.48B(11) [November 2009]

Files in This Item:

File Description SizeFormat
IJCB 48B(11) 1548-1557.pdf158.66 kBAdobe PDFView/Open
 Current Page Visits: 596 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 602940 since 06-Feb-2009  Last updated on 21-Oct-2014Webmaster: nopr@niscair.res.in