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IJEB Vol.44(05) [May 2006] >


Title: Analgesic activity of leaf extracts of Culcasia scandens P. Beauv
Authors: Okoli, C O
Akah, P A
Egbuniwe, O N
Keywords: Analgesic activity
Culcasia scandens
Issue Date: May-2006
Publisher: CSIR
Abstract: Analgesic activity of methanol leaf extract of C. scandens obtained by column chromatography and its graded solvent fractions, was evaluated in mice using acetic acid-induced abdominal writhing and formalin-induced paw licking. The extract and fractions significantly inhibited abdominal writhing and two phases of formalin-induced paw licking in mice, indicating that antinociceptive activity may involve inhibition of pain by peripheral and central mechanisms.
Page(s): 422-424
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.44(05) [May 2006]

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