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Title: Reaction and antimicrobial activity of 1-arylethylene benzofuranyl ketone derivatives
Authors: Micky, J A A
Saleh, N M
Mohamed, S M
Mohameda, S A
Salem, M M
Keywords: Benzalvisnaginone;naphthaquinone;2-aminothiazole chloroacetamide;antibacterial activity
Issue Date: Jun-2006
Publisher: CSIR
IPC Code: Int.Cl.8 C07D
Abstract: Interaction of benzalvisnaginone or khellinone derivatives with thiourea gives the tetrahydropyrimidin-2-thione derivatives which are condensed with chloroacetic acid in acetic anhydride to form thiazolo[3,2-]pytimidin-3-one. Its behaviour towards benzalde­hyde, and aromatic amine is discussed. While the reaction of the benzalvisnaginone derivative with quanidine yields 2-amino­pyrimidine and its reaction with 2,3-dichloro-1,4,- naphtha­quinone and 2-aminothiazole chloroacetamide, is investigated. The compounds are tested for their antibacterial activity.
Page(s): 1579-1583
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(06) [June 2006]

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