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Title: Steroid and aliphatic esters from the seeds of <i style="">Nigella sativa</i>
Authors: Mehta, B K
Gupta, Meenal
Verma, Manjul
Keywords: <i style="">Nigella sativa</i>
ergosta-5,24 (28)-dien-2,3-<i>cis</i>-diol
<i style=""> </i>ergosta-5,24 (28)-dien-2,3-<i>cis</i>-diol
pentyl undecanoate
pentyl undecanoate
Issue Date: Jun-2006
Publisher: CSIR
Series/Report no.: <b>Int.Cl.<sup>8</sup> C07C</b>
Abstract: Three novel compounds, one steroid and the other two aliphatic esters, have been isolated from the seeds of <i>Nigella sativa</i> and identified as ergosta-5,24 (28)-dien-2,3-<i>cis</i>-diol <b>1</b>, pentyl undecanoate <b>2</b>, methyloctadeca-14,16-dienoate <b>3</b>, on the basis of spectral and chemical analysis. The compound <b>2</b> exhibits significant activity against <i>Staphylococcus aureus</i> and <i>Shigella spp</i>, while moderate activity against <i>Escherichia coli </i>has been recorded. Rest of the compounds show poor activity against all the tested bacteria.
Description: 1567-1571
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(06) [June 2006]

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