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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(06) [June 2006] >
| Title: | Steroid and aliphatic esters from the seeds of Nigella sativa |
| Authors: | Mehta, B K
Gupta, Meenal
Verma, Manjul |
| Keywords: | Nigella sativa
ergosta-5,24 (28)-dien-2,3-cis-diol
ergosta-5,24 (28)-dien-2,3-cis-diol
pentyl undecanoate
pentyl undecanoate
methyloctadeca-14,16-dienoate |
| Issue Date: | Jun-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8 C07C |
| Abstract: | Three novel compounds, one steroid and the other two aliphatic esters, have been isolated from the seeds of Nigella sativa and identified as ergosta-5,24 (28)-dien-2,3-cis-diol 1, pentyl undecanoate 2, methyloctadeca-14,16-dienoate 3, on the basis of spectral and chemical analysis. The compound 2 exhibits significant activity against Staphylococcus aureus and Shigella spp, while moderate activity against Escherichia coli has been recorded. Rest of the compounds show poor activity against all the tested bacteria. |
| Page(s): | 1567-1571 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(06) [June 2006]
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