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IJC-B Vol.45B(06) [June 2006] >


Title: Steroid and aliphatic esters from the seeds of Nigella sativa
Authors: Mehta, B K
Gupta, Meenal
Verma, Manjul
Keywords: Nigella sativa
ergosta-5,24 (28)-dien-2,3-cis-diol
ergosta-5,24 (28)-dien-2,3-cis-diol
pentyl undecanoate
pentyl undecanoate
methyloctadeca-14,16-dienoate
Issue Date: Jun-2006
Publisher: CSIR
IPC CodeInt.Cl.8 C07C
Abstract: Three novel compounds, one steroid and the other two aliphatic esters, have been isolated from the seeds of Nigella sativa and identified as ergosta-5,24 (28)-dien-2,3-cis-diol 1, pentyl undecanoate 2, methyloctadeca-14,16-dienoate 3, on the basis of spectral and chemical analysis. The compound 2 exhibits significant activity against Staphylococcus aureus and Shigella spp, while moderate activity against Escherichia coli has been recorded. Rest of the compounds show poor activity against all the tested bacteria.
Page(s): 1567-1571
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.45B(06) [June 2006]

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