|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(05) [May 2006] >
| Title: | Synthesis and antibacterial screening of N-[Naphtho[1,2-b]pyrano[3,4-d]thiazol-8-yl] spiroindoloazetidin-2-ones/thiazolidin-4-ones |
| Authors: | Suryavanshi, Jitendra P
Pai, Nandini R |
| Keywords: | Naphthopyrans
azetidin-2-ones
thiazolidin-4-ones
2-oxo-1H-indole
antibacterial activity |
| Issue Date: | May-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8 C 07 D |
| Abstract: | 2-Amino-11-hydronaphtho[2,1:5,6]pyrano[4,3-d]thiazole 1a-d on treatment with isatin affords naphtho[1,2-b]pyrano[3,4-d]thiazolo-8-yl(3-imino-2-oxo-1H-indole 2a-d which on further reaction with chloroacetyl chloride and
mercaptoacetic acid yields the corresponding N-[naphtho[1,2-b]pyrano[3,4-d]thiazol-8-yl]spiro-[3H-indole-(1H,2H)-3,4-(2H)-3-chloroazetidin-2,2-diones 3a-d and N-[naphtho[1,2-b]pyrano[3,4-d]thiazol-8-yl]spiro-[3H-indole-(1H,2H)-3,2-(4H)-thiazolidine]-2,4-dione 4a-d. All the
compounds 2a-d, 3a-d and 4a-d have been
screened and found to possess considerable antibacterial activity. |
| Page(s): | 1227-1230 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(05) [May 2006]
|
|
