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IJC-B Vol.45B(05) [May 2006] >

Title: Synthesis of 2-(6-fluorobenzothiazole-2'-ylamino)-4-(phenylthioureido)-6-(substituted thioureido)-1,3,5-triazine as antimicrobial agent
Authors: Sareen, Vineeta
Khatri, Vineeta
Jain, Prakash
Sharma, Kanti
Keywords: Fluorobenzothiazole
triazine derivatives
anti­microbial activity
antifungal activity
phenyl thioureas
anti­microbial and antifungal activity
Issue Date: May-2006
Publisher: CSIR
IPC CodeInt.Cl.8 C 07 D
Abstract: 2,4,6-Trichloro-1,3,5-triazine has been reacted selectively with nucleophilic reagents, 6-Fluoro-2-aminobenzothiazole 1, phenyl thioureas 2 and different substituted thioureas 3 to give 2-(6-fluorobenzothiazole-2'-ylamino)-4-(phenylthioureido)-6-(substi­tuted thioureido)-1,3,5-triazine 4. These compounds are evaluated for their antimicrobial activity. The structure of all these compounds have been confirmed by IR, 1H NMR, mass spectral data and elemental analysis. Benzothiazoles, s-triazenes and thioureas exhibit various biological activities.
Page(s): 1288-1290
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.45B(05) [May 2006]

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