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Title: Synthesis of 2-(6-fluorobenzothiazole-2'-ylamino)-4-(phenylthioureido)-6-(substituted thioureido)-1,3,5-triazine as antimicrobial agent
Authors: Sareen, Vineeta
Khatri, Vineeta
Jain, Prakash
Sharma, Kanti
Keywords: Fluorobenzothiazole
triazine derivatives
anti­microbial activity
antifungal activity
phenyl thioureas
anti­microbial and antifungal activity
Issue Date: May-2006
Publisher: CSIR
Series/Report no.: <b>Int.Cl.<sup>8</sup> C 07 D </b>
Abstract: 2,4,6-Trichloro-1,3,5-triazine has been reacted selectively with nucleophilic reagents, 6-Fluoro-2-aminobenzothiazole <b style="">1</b>, phenyl thioureas <b style="">2</b> and different substituted thioureas <b style="">3</b> to give 2-(6-fluorobenzothiazole-2'-ylamino)-4-(phenylthioureido)-6-(substi­tuted thioureido)-1,3,5-triazine <b style="">4</b>. These compounds are evaluated for their antimicrobial activity. The structure of all these compounds have been confirmed by IR, <sup>1</sup>H NMR, mass spectral data and elemental analysis. Benzothiazoles, <i style="">s</i>-triazenes and thioureas exhibit various biological activities.
Description: 1288-1290
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(05) [May 2006]

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