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Title: Calcium chloride catalyzed three component, one-pot condensation reaction: An efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones
Authors: Gangadasu, B
Narender, P
Raju, B China
Rao, V Jayathirtha
Keywords: Biginelli reaction;dihydropyrimidinones;calcium chloride;economical and ecofriendly
Issue Date: May-2006
Publisher: CSIR
IPC Code: Int.Cl.8 C 07 D
Abstract: CaCl2 is an efficient, inexpensive and readily available catalyst for the three component, one-pot condensation reaction of an aldehyde, -ketoester and urea in refluxing ethanol to afford the corresponding dihydropyrimidinones in high yield. This method provides an envirofriendly, easy workup and isolation process.
Page(s): 1259-1263
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(05) [May 2006]

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