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dc.contributor.authorGupta, Shweta-
dc.contributor.authorMediratta, Pramod K-
dc.contributor.authorSingh, Surender-
dc.contributor.authorSharma, K K-
dc.contributor.authorShukla, Rimi-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.description.abstractAntihyperlipidaemic and antioxidant effect of Ocimum sanctum Linn. seed oil (OSSO) was investigated in rabbits. Administration of OSSO (0.8 g/kg body weight/day) for four weeks, in cholesterol (100 mg/kg body weight/day) fed rabbits significantly decreased serum cholesterol, triacylglycerol and LDL-+VLDL-cholesterol as compared to untreated cholesterol fed group. There was significant fall in atherogenic index in OSSO treated group. In addition, treatment with OSSO decreased lipid peroxidation and increased reduced glutathione content in blood. Antidiabetic effect of O. sanctum seed oil was evaluated in alloxan diabetic rabbits. Two weeks treatment of diabetic rabbits with OSSO (0.8 gm/kg/day) showed no significant hypoglycaemic effect. Results of the present study show that OSSO has hypocholesterolaemic and antioxidant effects but it does not have antidiabetic effect.en_US
dc.sourceIJEB Vol.44(04) [April 2006]en_US
dc.subjectAntioxidant activityen_US
dc.subjectHypocholesterolaemic agentsen_US
dc.subjectOcimum sanctumen_US
dc.subjectSeed oilen_US
dc.titleAntidiabetic, antihypercholesterolaemic and antioxidant effect of Ocimum sanctum (Linn) seed oilen_US
Appears in Collections:IJEB Vol.44(04) [April 2006]

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