Synthesis of pyrimidine based thiazolidinones and azetidinones: Antimicrobial and antitubercular agents

Abstract

Several 2-aryl-3-[4-(4-chlorophenyl)-6-(3,4,5-trimethoxy­phenyl)­pyrimidin-2-yl-ureido]-4-thiazolidinones <b style="">5a-j</b> and 1-[4-(4-chlorophenyl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-yl-ureido]-3-chloro-4-aryl-2-azetidinones <b style="">6a-j</b> have been synthesized and tested for their antibacterial, antifungal and antituberculosis activities against different microorganisms. The structures of novel synthesized compounds have been established on the basis of elemental analyses, ¹H NMR and IR spectral data.&nbsp;