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Title: Synthesis and antioxidant activities of some 4-benzylidenamino-4,5-dihydro- 1H-1,2,4-triazol-5-one derivatives
Authors: Yüksek, Haydar
Kolaylı, Sevgi
Küçük, Murat
Yüksek, M Ozgün
Ocak, Ummuhan
Şahinbaş, Esra
Sivrikaya, Efecan
Ocak, Miraç
Keywords: Antioxidant activities;pKa values;1,2,4-triazol-5-ones
Issue Date: Mar-2006
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D
Abstract: Eight 3-alkyl(aryl)-4-(3,4-dihydroxybenzylidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones 2 having 4,5-dihydro-1H-1,2,4-triazol-5-one ring are synthesized by the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones 1 with 3,4-dihydroxy-benzaldehyde and their antioxidant activities are investigated. In addition, compounds 2b, 2f and 2h are titrated potentiometrically with tetrabutylammonium hydroxide in non-aqueous solvents and the half-neutralization potential values and the corresponding pKa values are determined. The structures of new compounds are established from spectral data.
Page(s): 715-718
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(03) [March 2006]

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