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Title: Synthesis and antifungal activity of N-(alkyl/aryl)-2- (3-oxo-1,4-benzothiazin-2-yl)acetamide
Authors: Gupta, G
Wagh, S B
Keywords: N-(alkyl/aryl)-2-(3-oxo-1,4-benzothiazin-2-yl)acetamide
<i style="">o</i>-ATP
maleic anhydride
Issue Date: Mar-2006
Publisher: CSIR
Series/Report no.: <b>Int</b>.<b>Cl</b>.<b><sup>7</sup> C 07 D</b>
Abstract: A series of N-(alkyl/aryl)-2-(3-oxo-1,4-benzothiazin-2-yl)acetamide have been synthesized by condensation of substituted amines with maleic anhydride (MA) followed by cyclization with <i style="">o</i>-aminothiophenol (<i style="">o</i>-ATP). All the compounds have been screened for their antifungal activity against <i style="">Tricophyton rubrum</i>, <i style="">Epidermophyton floccosum</i> and <i style="">Malassazia furfur</i>. In the primary screening, some of the compounds exhibited appreciable activity. The structures of the synthesized compounds <b>7a-z</b> have been established on the basis of elemental analysis and spectral data.
Description: 697-702
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(03) [March 2006]

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