|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.44 [2006] >
IJEB Vol.44(02) [February 2006] >
| Title: | Modulation of serum cortisol by Substance P in albino rats: Evidence of a direct effect on adrenal gland |
| Authors: | Prasad, Anita
Naskar, Ranu
Dubey, Rakhi
Raha, Dipali
Ahmed, M Firoz |
| Keywords: | Cortisol
Regulatory role
Substance P |
| Issue Date: | Feb-2006 |
| Publisher: | CSIR |
| Abstract: | Effect of prolonged administration
of substance P on the plasma cortisol level in the albino rats has been
investigated. An inhibitory impact on intact individuals and a stimulatory
effect in pharmacologically annulled rats has been observed. It is concluded
that in normal conditions substance P presumably acts as a preventive agent for
any excess secretion of cortisol while during stress or disturbed HPA or RAS
conditions, it stimulates the secretion of cortisol. An intraglandular
modulatory role of substance P has been suggested. |
| Page(s): | 163-164 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.44(02) [February 2006]
|
|
