19-May-2013
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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(06) [June 2007] >
| Title: | Microwave-assisted synthesis and biological activity of 3-alkyl /aryl-6- (1-chloro-3,4-dihydronaphth- 2-yl)-5,6-dihydro-s- triazolo [3,4-b] [1,3,4] thiadiazoles |
| Authors: | Kamotra, Poonam
Gupta, Avinash K
Gupta, Rajive
Somal, P
Singh, S |
| Keywords: | 3-Alkyl/aryl-6-(1-chloro-3,4-dihydronaphth-2-yl)-5
6-Dihydro-s-triazolo[3,4-b][1,3,4]thiadiazoles
p-TsOH
Microwave irradiation
Rate enhancement
Specific microwave effect
Biological activity |
| Issue Date: | Jun-2007 |
| Publisher: | CSIR |
| Abstract: | 3-Alkyl/aryl-6-(1-chloro-3,4-dihydronaphth-2-yl)- 5,6-dihydro-s-triazolo[3,4-b][1,3,4] thiadiazoles 3 have been synthesised by the condensation of 5-alkyl/aryl-4-amino-3-mercapto-1,2,4- triazoles 2 with 1-chloro-2-formyl-3,4-dihydronaphthalene 1 in presence of catalytic quantity of p-TsOH under microwave irradiation. Rate enhancement and improvement in yields, characteristics of synthesis under microwave irradiation, have been observed. The compounds synthesised have been characterised and screened for their antibacterial, antifungal, antiinflammatory and antioxidant activity. |
| Page(s): | 980-984 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(06) [June 2007]
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