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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(06) [June 2007] >
| Title: | Synthesis of conformationally constrained ⍺-imino acid derivatives via ring-closing metathesis |
| Authors: | Kotha, Sambasivarao
Khedkar, Priti |
| Keywords: | Peptidomemitics
Conformationally constrained amino acids
Conformationally constrained imino acids
Ring-closing metathesis |
| Issue Date: | Jun-2007 |
| Publisher: | CSIR |
| Abstract: | Conformationally constrained amino acid derivatives are useful in the synthesis of peptidomimetics. Seven-, and eight-membered conformationally constrained ⍺-imino acid derivatives have been prepared via RCM (ring-closing metathesis). Interestingly, attempts to achieve the synthesis of nine-membered imino acid derivative resulted in the formation of dimeric, 18-membered macrocyclic bis-⍺-imino acid derivative. |
| Page(s): | 975-979 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(06) [June 2007]
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