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|Title: ||Pharmacognosy and biological activity of Cordia rothii Roem. & Schult. bark|
|Authors: ||Chauhan, Malati G|
Chavan, Sulakshan S
|Keywords: ||Cardiotonic activity|
|Issue Date: ||Oct-2009|
|Series/Report no.: ||Int. Cl.8: A01K61/00, A61P9/00, A61P9/04, A61P9/06|
Cordia rothii Roem. & Schult. bark has reputation of being
effective in heart ailments in Saurashtra region of Gujarat.
The investigation was undertaken to study the microscopy, chemical constituents
and pharmacological actions of Cordia
rothii Roem. & Schult. bark. Phytochemical analysis of different bark
extracts revealed the presence of alkaloids, glycoalkaloids, coumarins and
inorganic salts. The aqueous extract of the bark was found to produce
significant increase in force of contraction along with chronotropic effects on
isolated rat heart preparations. The same extract did not show increase in
urine output, however a significant increase in sodium as well as potassium
excretion was noticed. Alcoholic extract was found to decrease glucose levels
as compared to control. The study corroborates the cardiotonic activity
attributed to Cordia rothii bark.
|ISSN: ||0975-1068 (Online); 0972-5938 (Print)|
|Appears in Collections:||IJTK Vol.08(4) [October 2009]|
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