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IJTK Vol.08(4) [October 2009] >

Title: Pharmacognosy and biological activity of Cordia rothii Roem. & Schult. bark
Authors: Chauhan, Malati G
Chavan, Sulakshan S
Keywords: Cardiotonic activity
Cordia rothii
Issue Date: Oct-2009
Publisher: CSIR
IPC CodeInt. Cl.8: A01K61/00, A61P9/00, A61P9/04, A61P9/06
Abstract:  Cordia rothii Roem. & Schult. bark has reputation of being effective in heart ailments in Saurashtra region of Gujarat. The investigation was undertaken to study the microscopy, chemical constituents and pharmacological actions of Cordia rothii Roem. & Schult. bark. Phytochemical analysis of different bark extracts revealed the presence of alkaloids, glycoalkaloids, coumarins and inorganic salts. The aqueous extract of the bark was found to produce significant increase in force of contraction along with chronotropic effects on isolated rat heart preparations. The same extract did not show increase in urine output, however a significant increase in sodium as well as potassium excretion was noticed. Alcoholic extract was found to decrease glucose levels as compared to control. The study corroborates the cardiotonic activity attributed to Cordia rothii bark.
Page(s): 598-601
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Source:IJTK Vol.08(4) [October 2009]

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