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IJC-B Vol.46B(05) [May 2007] >

Title: Synthesis and fungicidal activity of some 3-(5-aryl-1,3,4-thiadiazol-2-yl)-1- (β-D-glucopyranosyl)-5-alkyl- 2-thio-4-imidazolidinones
Authors: Srivastava, Alok Kumar
Khare, R K
Singh, H
Keywords: Thiadiazole
Cephalosporium sacchari
Colletotrichum falcate
Helminthosporium oryzae
Issue Date: May-2007
Publisher: CSIR
IPC CodeInt.Cl.⁸ C07D
Abstract: 3-(5-Aryl-1,3,4-thiadiazol-2-yl)-1-(-β-D-glucopyranosyl)-5-alkyl-2-thio-4-imidazolidinones 5 have been conveniently prepared from 3-(5-aryl-1,3,4-thiadiazol-2-yl)-5-alkyl-2-thio-4-imidazolidinones 3 by reaction of β-D-1,2,3,4,6-penta-O-acetylglucopyranose and iodine. Compounds 3 are synthesized by reported method from N-(5-aryl-1,3,4-thiadiazol-2-yl) thioureas 2 and ⍺-chloroalkanoic acid in dry pyridine. All the compounds have been tested in vitro for their antifungal activity against the two fungal species Cephalosporium sacchari, Colletotrichum falcate and Helminthosporium oryzae.
Page(s): 875-879
ISSN: 0376-4699
Source:IJC-B Vol.46B(05) [May 2007]

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