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Title: Synthesis of 5-arylidene-2-aryl-3-(benzotriazoloacetamidyl)-1,3-thiazolidin-4-ones as analegesic and antimicrobial agents
Authors: Asati, K C
Srivastava, S K
Srivastava, S D
Keywords: Thiazolidinon-arylidenes
analgesic agents
anti­microbial agents
ethyl chloroacetate
Issue Date: Feb-2006
Publisher: CSIR
Series/Report no.: <b>Int</b>.<b>Cl</b>.<b><sup>7</sup> C 07 D</b>
Abstract: Benzotriazole on reaction with ethyl chloroacetate affords <b>1</b>, which on treatment with hydrazine hydrate yields <b>2</b>. Condensation of N<sup>1</sup>(acetohydrazido)benzotriazole <b>2 </b>with various carbonyls gives arylidene acetohydrazido benzotriazoles <b>3</b> which on cycloaddition with mercaptoacetic acid yields the corresponding 4-thia­zoli­dinones <b>4</b>. which on reaction with various carbonyl compounds afford 5-arylidene-2-aryl-benzotriazoloacetamidyl-1,3-thiazolidin-4-ones <b>5</b>.
Description: 526-531
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(02) [February 2006]

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