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IJC-B Vol.45B(02) [February 2006] >

Title: Synthesis of 5-arylidene-2-aryl-3-(benzotriazoloacetamidyl)-1,3-thiazolidin-4-ones as analegesic and antimicrobial agents
Authors: Asati, K C
Srivastava, S K
Srivastava, S D
Keywords: Thiazolidinon-arylidenes
analgesic agents
anti­microbial agents
ethyl chloroacetate
Issue Date: Feb-2006
Publisher: CSIR
IPC CodeInt.Cl.7 C 07 D
Abstract: Benzotriazole on reaction with ethyl chloroacetate affords 1, which on treatment with hydrazine hydrate yields 2. Condensation of N1(acetohydrazido)benzotriazole 2 with various carbonyls gives arylidene acetohydrazido benzotriazoles 3 which on cycloaddition with mercaptoacetic acid yields the corresponding 4-thia­zoli­dinones 4. which on reaction with various carbonyl compounds afford 5-arylidene-2-aryl-benzotriazoloacetamidyl-1,3-thiazolidin-4-ones 5.
Page(s): 526-531
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.45B(02) [February 2006]

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