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IJC-B Vol.45B(02) [February 2006] >

Title: Synthesis of new 1, 10-diethoxy-1H-pyrano[4, 3-b]quinolines and their antibacterial studies
Authors: Dhanabal, T
Suresh, T
Mohan, P S
Keywords: Hydroxyquinaldines
Vilsmeier Reaction
diethoxy-1H-pyrano[4, 3-b]quinolines
anti-bacterial activity
Issue Date: Feb-2006
Publisher: CSIR
IPC CodeInt.Cl.7 C 07 D
Abstract: A simple and one-pot synthesis of 1, 10-diethoxy-1H-pyrano[4, 3-b]quinolines 3a-e from the respective 4-chloro-3-formyl-2-(2-hydroxyethen-1-yl)quinolines 2a-e has been achieved (by Vilsmeier’s reaction on 4-hydroxyquinaldines) by way of intramolecular cyclization when reacted with ethanol in the presence of a few drops of hydrochloric acid. All the newly synthesized compounds have been characterized by their spectral and analytical data. Anti-bacterial studies also have been carried out for some of the synthesized compounds.
Page(s): 523-525
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.45B(02) [February 2006]

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