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IJC-B Vol.45B [2006] >
IJC-B Vol.45B(02) [February 2006] >


Title: Solvent-free improved syntheses of some substituted 1, 3-diaryl-propenones and 3,5-diaryl-6-carbethoxycyclohexenones under microwave irradiation and their antibacterial activity
Authors: Jhala, Yajuvendra S
Dulawat, Shiv S
Verma, B L
Keywords: Microwave
Solvent-free syntheses
3, 5-diaryl-6-carbethoxycyclohexenones
antibacterial activity
Issue Date: Feb-2006
Publisher: CSIR
IPC CodeInt.Cl.7 C 07 C
Abstract: Microwave induced solvent-free solid phase syntheses of substituted 1,3-diarylpropenones (chalcones) 3a-f using basic alumina and their subsequent rapid transformation to 3,5-diaryl-6-carbethoxycyclohexenones 4a-f with ethyl acetoacetate in the presence of basic alumina and piperidine under solvent free condition using domestic microwave oven has been described. This process has advantages over conventional methods such as shorter reaction time, higher yields and environmental acceptability. All the synthesized compounds have been screened for their antibacterial activity.
Page(s): 466-469
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.45B(02) [February 2006]

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