Please use this identifier to cite or link to this item:
Title: Propionic acids in organic synthesis: Novel synthesis of benzimidazole, 3,1-benzoxazine, 3-aminoquinazoline and 3-aminothieno[2,3-d]pyrimidine derivatives containing 2-naphthyl propionyl moiety
Authors: Al-Sehemi, Abdullah G M
El-Sharief, A M Sh
Ammar, Y A
Keywords: Propionic acids;benzimidazole;benzoxazine;aminoquinazoline;aminothieno pyrimidine;naphthyl propionyl moiety;ammonium thiocyanate;sodium azide
Issue Date: Feb-2006
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D
Abstract: Naproxenoyl chloride 2 is reacted with some nucleophilic reagents as ammonium thiocyanate and sodium azide to produce the novel isothiocyanate 3 and azide 4 derivatives, respectively. Interaction of isothiocyanate 3 with 1,2-phenylenediamine and anthranilic acid has produced the corresponding benzimidazole 5 and 3,1-benzoxazine 7 derivatives, respectively. Treatment of acid azide 4 with p-toluidine afforded urea derivative 9. The novel quinazolinone 11 was synthesized by acylation of methyl anthranilate with acid chloride 2 followed by treatment with hydrazine hydrate.
Page(s): 450-455
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(02) [February 2006]

Files in This Item:
File Description SizeFormat 
IJCB 45B(2) 450-455.pdf127.01 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.