|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(02) [February 2006] >
| Title: | Propionic acids in organic synthesis: Novel synthesis of benzimidazole, 3,1-benzoxazine, 3-aminoquinazoline and 3-aminothieno[2,3-d]pyrimidine derivatives containing 2-naphthyl propionyl moiety |
| Authors: | Al-Sehemi, Abdullah G M
El-Sharief, A M Sh
Ammar, Y A |
| Keywords: | Propionic acids
benzimidazole
benzoxazine
aminoquinazoline
aminothieno pyrimidine
naphthyl propionyl moiety
ammonium thiocyanate
sodium azide |
| Issue Date: | Feb-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D |
| Abstract: | Naproxenoyl chloride 2 is reacted with some nucleophilic reagents as ammonium thiocyanate and sodium azide to produce the novel isothiocyanate 3 and azide 4 derivatives, respectively. Interaction of isothiocyanate 3 with 1,2-phenylenediamine and anthranilic acid has produced the corresponding benzimidazole 5 and 3,1-benzoxazine 7 derivatives, respectively. Treatment of acid azide 4 with p-toluidine afforded urea derivative 9. The novel quinazolinone 11 was synthesized by acylation of methyl anthranilate with acid chloride 2 followed by treatment with hydrazine hydrate. |
| Page(s): | 450-455 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(02) [February 2006]
|
|
