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Title: Synthesis of pyrazolines promoted by Amberlyst-15 catalyst
Authors: Holla, B Shivarama
Mahalinga, M
Poojary, Boja
Ashok, Mithun
Akberali, P M
Keywords: Pyrazolines;propenones;cyclization;Amberlyst–15 catalyst
Issue Date: Feb-2006
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D
Abstract: The condensation of a series of aromatic ketones with aromatic aldehydes under aldol conditions affords 1-aryl-3-(substituted­phenyl/phenyl furanyl/thienyl)-2-propen-1-ones 1. The resulting propenones undergo facile and clean cyclization with hydrazine and substituted hydrazine derivatives to yield 3-aryl-5-(substituted­phenyl/phenylfuranyl/thienyl)-2-pyrazolines 2. This reaction is carried out in the presence of Amberlyst–15 catalyst to afford the above pyrazolines 2 in considerably good yield. All the synthesized compounds have been characterized by spectral studies.
Page(s): 568-571
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(02) [February 2006]

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