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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(01) [January 2006] >
| Title: | Novel approach for the rapid and efficient synthesis of heterocyclic Schiff bases and azetidinones under microwave irradiation |
| Authors: | Naik, Bhanvesh
Desai, K R |
| Keywords: | Schiff base
azetidinone
microwave
antibacterial activity |
| Issue Date: | Jan-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D |
| Abstract: | A series of compounds, viz. 3′′-chloro-4′′-(substituted
phenyl)-1′′-[4-(coumarin-3-yl)thiazol-2-yl]-2′′-azetidinones 4a-j have been prepared by the reaction
of 2-N-(substituted benzylidene)imino-4-(coumarin-3-yl)thiazoles 3a-j with chloroacetyl chloride in the
presence of triethylamine. The Schiff bases
3a-j have been prepared by
the condensation of 2-amino-4-(coumarin-3-yl)thiazole 1 with different aldehydes 2.
Both the reactions are carried out by conventional and microwave methods. The
products are screened for their antibacterial activity against Staphylococcus aureus, Bacillus subtillis,
Escherichia coli and Salmonella typhi |
| Page(s): | 267-271 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(01) [January 2006]
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