NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(10) [October 2009] >

Title: A convenient synthesis of 2(2-benzo[b]furo)indoles and benzofuropyrazoles
Authors: Goudarshivannanavar, B C
Jayadevappa, H
Mahadevan, K M
Keywords: 2-Acetylbenzofuran
phenylhydrazine hydrochloride
zinc chloride
Fisher indole synthesis
Vilsmeier-Haack reaction
Issue Date: Oct-2009
Publisher: CSIR
Abstract: A short synthesis of benzo[b]furo indolyls 3a-g from 2-acetylbenzofuran 1 in two steps and corresponding pyrazoles 4a-g is described. An interesting scale-up procedure for the synthesis of 2-acetylbenzofuran is also been reported. Similarly 2-acetylbenzofurohydrazones 2a-g is prepared from 2-acetyl benzofuran and with various phenylhydrazine hydrochlorides in presence of CH3COONa/EtOH at RT in excellent yield (90-95%). These 2-acetyl benzofurohydrazones 2a-g are subjected to Fischer indole cyclisation in presence of ZnCl2 in acetonitrile as solvent to get 2(2-benzo[b]furo)indoles 3a-g in good yield.
Page(s): 1419-1423
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.48B(10) [October 2009]

Files in This Item:

File Description SizeFormat
IJCB 48B(10) 1419-1423.pdf49.96 kBAdobe PDFView/Open
 Current Page Visits: 109 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 167101 since 01-Sep-2015  Last updated on 28-Jun-2016Webmaster: