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Title: Microwave assisted synthesis of 1,3,4-oxadiazolyl 1, 8-naphthyridines under solvent-free conditions using solid support
Authors: Mogilaiah, K
Swamy, T Kumara
Chandra, A Vinay
Srivani, N
Keywords: 1,3,4 Oxadiazole;1,8 naphthyridine;acetophenones;hydrazone;acetic anhydride;silica gel;solid support;microwave irradition;solvent-free condition
Issue Date: Oct-2009
Publisher: CSIR
Abstract: A convient synthesis of 1-(4-acetyl-5-aryl-5-methyl-[1,3, 4]oxadiazol-2-ylmethyl)-3-(4-chlorophenyl)-1H-[1, 8]naphthyri­din-2-ones, by cyclization of acetophenone [2-oxo-3-(4-chloro­phenyl)-2H-[1,8]-naphthyridin-1-yl]methylcarbonyl­hydra­zones with acetic anhydride using silica gel as solid support under microwave irradition is described. The structural assignments of the compounds are based on their elemental analyses and spectral data.
Page(s): 1462-1465
ISSN: 0975-0983(Online); 0376-4699(Print
Appears in Collections:IJC-B Vol.48B(10) [October 2009]

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