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IJC-B Vol.48B [2009] >
IJC-B Vol.48B(10) [October 2009] >

Title: Microwave assisted synthesis of 1,3,4-oxadiazolyl 1, 8-naphthyridines under solvent-free conditions using solid support
Authors: Mogilaiah, K
Swamy, T Kumara
Chandra, A Vinay
Srivani, N
Keywords: 1,3,4 Oxadiazole
1,8 naphthyridine
acetic anhydride
silica gel
solid support
microwave irradition
solvent-free condition
Issue Date: Oct-2009
Publisher: CSIR
Abstract: A convient synthesis of 1-(4-acetyl-5-aryl-5-methyl-[1,3, 4]oxadiazol-2-ylmethyl)-3-(4-chlorophenyl)-1H-[1, 8]naphthyri­din-2-ones, by cyclization of acetophenone [2-oxo-3-(4-chloro­phenyl)-2H-[1,8]-naphthyridin-1-yl]methylcarbonyl­hydra­zones with acetic anhydride using silica gel as solid support under microwave irradition is described. The structural assignments of the compounds are based on their elemental analyses and spectral data.
Page(s): 1462-1465
ISSN: 0975-0983(Online); 0376-4699(Print
Source:IJC-B Vol.48B(10) [October 2009]

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