Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/6112
Title: Synthesis of 6,7-dihydroxy-3-aryl-5-undecyl-4,1,2-benzoxadiazines
Authors: Brahmeshwari, G
Keywords: Embelin
acid hydrazides
acetylation
cyclization reaction
antibacterial
antifungal
Issue Date: Oct-2009
Publisher: CSIR
Abstract: <smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="metricconverter"> Condensation of Embelin <b>1</b> with different aromatic acid hydra­zides <b>2</b> in glacial acetic acid to give N<sup>1</sup>-5-hydroxy-6-unde­cyl-<i>p</i>-benzoaquinone-2-yl)-benzohydrides <b>3</b>. Reductive cycli­za­tion of the product <b>3</b> with simultaneous acetylation <i>in situ</i> resulted in the formation of the compound <b>4</b> 1-N-acetyl-6,7-diacetyl-3-aryl-5-undecyl-4,1,2-benzoxadiazine. In the final step the compound <b>4</b> is deacetylated to give the title products <b>5</b>. The structures of the newly prepared compounds have been confirmed from analytical and spectral data. Some of the compounds exhibited antibacterial and antifungal activity. </smarttagtype>
Description: 1457-1461
URI: http://hdl.handle.net/123456789/6112
ISSN: 0975-0983(Online); 0376-4699(Print
Appears in Collections:IJC-B Vol.48B(10) [October 2009]

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