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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(10) [October 2009] >
| Title: | Synthesis of 6,7-dihydroxy-3-aryl-5-undecyl-4,1,2-benzoxadiazines |
| Authors: | Brahmeshwari, G |
| Keywords: | Embelin
acid hydrazides
acetylation
cyclization reaction
antibacterial
antifungal |
| Issue Date: | Oct-2009 |
| Publisher: | CSIR |
| Abstract: | Condensation of Embelin 1 with different aromatic acid hydrazides 2 in glacial acetic acid to give N1-5-hydroxy-6-undecyl-p-benzoaquinone-2-yl)-benzohydrides 3. Reductive cyclization of the product 3 with simultaneous acetylation in situ resulted in the formation of the compound 4 1-N-acetyl-6,7-diacetyl-3-aryl-5-undecyl-4,1,2-benzoxadiazine. In the final step the compound 4 is deacetylated to give the title products 5. The structures of the newly prepared compounds have been confirmed from analytical and spectral data. Some of the compounds exhibited antibacterial and antifungal activity. |
| Page(s): | 1457-1461 |
| ISSN: | 0975-0983(Online); 0376-4699(Print |
| Source: | IJC-B Vol.48B(10) [October 2009]
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