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IJC-B Vol.48B(09) [September 2009] >


Title: Synthesis and antioxidant activity of indolyl chromenes
Authors: Shanthia, Gnanamani
Perumal, Paramasivan T
Rao, Urmila
Sehgal, Praveen Kumar
Keywords: Indolyl chromenes
l-proline
antioxidant
reducing power
radical scavenging
Issue Date: Sep-2009
Publisher: CSIR
Abstract: A simple and efficient method for the synthesis of indolyl chromenes 4a-h has been accomplished by the one-pot three-component reaction of salicylaldehyde and malononitrile with indole catalyzed by l-proline in water. All the synthesized compounds are evaluated for antioxidant activity. All of the compounds 4a-h exhibited excellent free radical scavenging activity and found to be more potent than the standard. Compounds 4b-c and 4h showed very high reducing power
Page(s): 1319-1323
Source:IJC-B Vol.48B(09) [September 2009]

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