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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(09) [September 2009] >
| Title: | Synthesis and antioxidant activity of indolyl chromenes |
| Authors: | Shanthia, Gnanamani
Perumal, Paramasivan T
Rao, Urmila
Sehgal, Praveen Kumar |
| Keywords: | Indolyl chromenes
l-proline
antioxidant
reducing power
radical scavenging |
| Issue Date: | Sep-2009 |
| Publisher: | CSIR |
| Abstract: | A simple and
efficient method for the synthesis of indolyl chromenes 4a-h has been accomplished by the one-pot three-component reaction
of salicylaldehyde and malononitrile with indole catalyzed by l-proline
in water. All the synthesized compounds are evaluated for antioxidant activity.
All of the compounds 4a-h exhibited
excellent free radical scavenging activity and found to be more potent than the
standard. Compounds 4b-c and 4h showed very high reducing power |
| Page(s): | 1319-1323 |
| Source: | IJC-B Vol.48B(09) [September 2009]
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