Please use this identifier to cite or link to this item:
Title: Synthesis of pharmaceutically important 1,3,4-thiadiazole and imidazolinone derivatives as antimicrobials
Authors: Amir, Mohd
Kumar, Arun
Ali, Israr
Khan, S A
Keywords: Aminobenzothiazole
Issue Date: Sep-2009
Publisher: CSIR
Abstract: Thiosemicarbazide of 6-chloro-2-aminobenzothiozole on cyclization with different aromatic carboxylic acids in POCl<sub>3</sub> and substituted azlactones in pyridine provide the corresponding 2-aryl-5-(6′-chloro-1′,3′-benzothiazole-2-yl-amino)-1,3,4-thiadiazoles <b>2a-j </b>and 4-(4′-arylidene) -2-phenyl-1-(6′-chloro-1′,3′-benzothiazol-2-yl-thiourido)-4,5-dihydroimidazolin-5-ones <b>3a-e</b>. The compounds have been characterized by elemental analysis, IR, <sup>1</sup>H NMR and mass spectral data. All the compounds have been evaluated <i>in vitro</i> for their antimicrobial activities against several microbes and show significant activity
Description: 1288-1293
Appears in Collections:IJC-B Vol.48B(09) [September 2009]

Files in This Item:
File Description SizeFormat 
IJCB 48B(09) 1288-1293.pdf148.76 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.