Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/6046
Title: Synthesis of pharmaceutically important 1,3,4-thiadiazole and imidazolinone derivatives as antimicrobials
Authors: Amir, Mohd
Kumar, Arun
Ali, Israr
Khan, S A
Keywords: Aminobenzothiazole
1,3,4-thiadiazole
imidazolinone
antimicrobial
Issue Date: Sep-2009
Publisher: CSIR
Abstract: Thiosemicarbazide of 6-chloro-2-aminobenzothiozole on cyclization with different aromatic carboxylic acids in POCl<sub>3</sub> and substituted azlactones in pyridine provide the corresponding 2-aryl-5-(6′-chloro-1′,3′-benzothiazole-2-yl-amino)-1,3,4-thiadiazoles <b>2a-j </b>and 4-(4′-arylidene) -2-phenyl-1-(6′-chloro-1′,3′-benzothiazol-2-yl-thiourido)-4,5-dihydroimidazolin-5-ones <b>3a-e</b>. The compounds have been characterized by elemental analysis, IR, <sup>1</sup>H NMR and mass spectral data. All the compounds have been evaluated <i>in vitro</i> for their antimicrobial activities against several microbes and show significant activity
Description: 1288-1293
URI: http://hdl.handle.net/123456789/6046
Appears in Collections:IJC-B Vol.48B(09) [September 2009]

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