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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(09) [September 2009] >
| Title: | Synthesis of pharmaceutically important 1,3,4-thiadiazole and imidazolinone derivatives as antimicrobials |
| Authors: | Amir, Mohd
Kumar, Arun
Ali, Israr
Khan, S A |
| Keywords: | Aminobenzothiazole
1,3,4-thiadiazole
imidazolinone
antimicrobial |
| Issue Date: | Sep-2009 |
| Publisher: | CSIR |
| Abstract: | Thiosemicarbazide of
6-chloro-2-aminobenzothiozole on cyclization with different aromatic carboxylic
acids in POCl3 and substituted azlactones in pyridine provide the
corresponding
2-aryl-5-(6′-chloro-1′,3′-benzothiazole-2-yl-amino)-1,3,4-thiadiazoles 2a-j and
4-(4′-arylidene)
-2-phenyl-1-(6′-chloro-1′,3′-benzothiazol-2-yl-thiourido)-4,5-dihydroimidazolin-5-ones
3a-e. The compounds have been characterized by elemental analysis, IR, 1H
NMR and mass spectral data. All the compounds have been evaluated in vitro
for their antimicrobial activities against several microbes and show
significant activity |
| Page(s): | 1288-1293 |
| Source: | IJC-B Vol.48B(09) [September 2009]
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