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Indian Journal of Biotechnology (IJBT) >
IJBT Vol.03 [2004] >
IJBT Vol.03(3) [July 2004] >
| Title: | Production of camptothecines from callus cultures of Nothapodytes foetida (Wight) Sleumer |
| Authors: | Sundravelan, R
Desireddy, B
Ciddi, Veeresham |
| Keywords: | Nothapodytes foetida
camptothecine
9-methoxy camptothecine |
| Issue Date: | Jul-2004 |
| Publisher: | CSIR |
| IPC Code: | Int. Cl.7 A 01 H 4/00; A 01 N 63/00 |
| Abstract: | Murashige and Skoog (MS) medium supplemented with picloram (2 mg/l), N6- benzyladenine(BA) (1 mg/l) and gibberellic acid (GA3) (1 mg/l) was found to be suitable for the establishment of callus cultures from leaves of Nothapodytes foetida (Wight) Sleumer. The callus upon extraction and analysis revealed the presence of a cytotoxic quinoline alkaloid, camptothecine (CPT) (2.893±2.38 mg %) and 9-methoxy camptothecine (MCPT) (0.4±0.4 mg %). |
| Page(s): | 452-453 |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Source: | IJBT Vol.03(3) [July 2004]
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