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Title: Production of camptothecines from callus cultures of <i style="">Nothapodytes foetida</i> (Wight) Sleumer
Authors: Sundravelan, R
Desireddy, B
Ciddi, Veeresham
Keywords: <i style="">Nothapodytes foetida</i>
9-methoxy camptothecine
Issue Date: Jul-2004
Publisher: CSIR
Series/Report no.: Int. Cl.<sup>7</sup> A 01 H 4/00; A 01 N 63/00
Abstract: Murashige and Skoog (MS) medium supplemented with picloram (2 mg/l), N<sup>6</sup>- benzyladenine(BA) (1 mg/l) and gibberellic acid (GA<sub>3</sub>) (1 mg/l) was found to be suitable for the establishment of callus cultures from leaves of <i style="">Nothapodytes foetida</i> (Wight) Sleumer. The callus upon extraction and analysis revealed the presence of a cytotoxic quinoline alkaloid, camptothecine (CPT) (2.893±2.38 mg %) and 9-methoxy camptothecine (MCPT) (0.4±0.4 mg %).
Description: 452-453
ISSN: 0975-0967 (Online); 0972-5849 (Print)
Appears in Collections:IJBT Vol.03(3) [July 2004]

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