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Title: Production of camptothecines from callus cultures of Nothapodytes foetida (Wight) Sleumer
Authors: Sundravelan, R
Desireddy, B
Ciddi, Veeresham
Keywords: Nothapodytes foetida
9-methoxy camptothecine
Issue Date: Jul-2004
Publisher: CSIR
IPC CodeInt. Cl.7 A 01 H 4/00; A 01 N 63/00
Abstract: Murashige and Skoog (MS) medium supplemented with picloram (2 mg/l), N6- benzyladenine(BA) (1 mg/l) and gibberellic acid (GA3) (1 mg/l) was found to be suitable for the establishment of callus cultures from leaves of Nothapodytes foetida (Wight) Sleumer. The callus upon extraction and analysis revealed the presence of a cytotoxic quinoline alkaloid, camptothecine (CPT) (2.893±2.38 mg %) and 9-methoxy camptothecine (MCPT) (0.4±0.4 mg %).
Page(s): 452-453
ISSN: 0975-0967 (Online); 0972-5849 (Print)
Source:IJBT Vol.03(3) [July 2004]

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