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Title: Mixed ligand complex of monovalent copper with benzimidazole derivatives and alanine: Synthesis, characterization and antimicrobial studies
Authors: Yadav, Poonam
Sharma, Shobhana
Kumari, Suman
Ranka, Mamta
Keywords: Mixed ligand complex;Azomethine;Benzimidazole;Alanine;Antibacterial;Antifungal
Issue Date: Dec-2021
Publisher: NIScPR-CSIR, India
Abstract: xed ligand complexes of transition metal ions exhibit broad range of biological activities. Schiff bases containing azomethine (C=N) group and amino acids are versatile compounds for design of ternary complexes. An attempt has been made to synthesize novel copper(I) complex by the reaction of two ligands, 2-N-(4-methyl phenyl ethanimine) benzimidazole [MPEIBI] as L1 and an amino acid Alanine as L2, and freshly prepared cuprous chloride solution in 1:1:1 molar ratio through conventional reflux method. The synthesized ligand and copper(I) complex are characterized by elemental analysis, molecular weight determination, magnetic moment measurement, spectroscopic techniques. These synthesized compounds were evaluated for antimicrobial studies against bacterial strains, B. subtilis, E. coli and fungal pathogens, T. ressei, C. albicans. The Cu(I) complex has shown remarkable antibacterial and antifungal activity.
Page(s): 1539-1544
ISSN: 0975-1017 (Online); 0971-4588 (Print)
Appears in Collections:IJC-A Vol.60A(12) [December 2021]

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