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Title: Synthesis, crystal structure and fluorescence spectrum of some new 1,2,3-triazolxanthen-3-one derivatives
Authors: Dong, Hong-Ru
Jin, Chi-Qiong
Chen, Zi-Bao
Keywords: Xanthen-3-one;crystal structure;synthesis;fluorescence spectra;inhibiting HIV-1 protease;1H-1,2,3-triazole
Issue Date: Dec-2021
Publisher: NIScPR-CSIR, India
Abstract: Some new compounds 9-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)-6-hydroxy-3H-xanthen-3-one 7a-j have been synthesized for new fluorescence probe material. Their fluorescence and ultraviolet-visible spectra have been studied. Their structures are established by MS, IR and 1H NMR spectral data. The structure of title compound 7c has been identified by X-ray diffraction. C22H14C1N3O3, belongs to triclinic system, space group Pī with a = 8.296(4), b = 9.726(5), c = 11.976(6) Å, α = 90.953(7), β = 105.081(7), γ = 100.693(8)º, V = 914.7(8)Å3, Z = 2, Dc = 1.466 Mg/m3, F(000) = 416.0 and μ = 0.240 mm–1. The title compound has a weaker inhibiting HIV-1 protease than indinavir.
Page(s): 1629-1635
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.60B(12) [December 2021]

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