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Title: Enantioselective synthesis of bronchodilating agent (R)-Salmeterol #
Authors: Ranganath, P L N
Anil, T
Narsaiah, A Venkat
Keywords: Enantioselective;amino alcohol;catecholamines;branchospasm;dihydroxylation
Issue Date: Oct-2021
Publisher: NIScPR-CSIR, India
Abstract: Synthesis of β2-adrenoreceptor agonist bronchodilator (R)-Salmeterol has been described with good yields. The synthesis commenced from commercially available starting materials, 4-hydroxy benzaldehyde and phenylbutanoic acid. The features of the synthetic strategy are Wittig olefination and Sharpless asymmetric dihydroxylation.
Page(s): 1347-1352
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.60B(10) [October 2021]

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