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http://nopr.niscpr.res.in/handle/123456789/58322| Title: | An efficient solvent-free synthesis of pyrido[2,3-d]pyrimidine derivatives utilizing lactic acid as green and eco-friendly catalyst |
| Authors: | Safarzaei, Mohyeddin Mollashahi, Ebrahim Lashkari, Mojtaba Maghsoodlou, Malek Taher Hazeri, Nourallah |
| Keywords: | Lactic acid;6-amino-1;3-dimethyluracil;aryl aldehyde;malononitrile;solvent-free conditions |
| Issue Date: | Oct-2021 |
| Publisher: | NIScPR-CSIR, India |
| Abstract: | An efficient, solvent-free and one-pot procedure for the synthesis of pyrido[2,3-d]pyrimidine derivatives by condensation of aromatic aldehydes, malononitrile and 6-amino-1,3-dimethyl uracil at 90°C catalyzed by lactic acid as an inexpensive, biological and eco-friendly compound is described. The remarkable benefits of this procedure are green and environmentally friendly reaction conditions, high yields, short reaction time, simple methodology and easy workup. |
| Page(s): | 1368-1372 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.60B(10) [October 2021] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJC (Section B), 60B, 1368-1372 (Oct,2021).pdf | 645.89 kB | Adobe PDF | View/Open |
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