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Title: Synthesis and spectroscopic investigation of binding of novel Thiazolo [2, 3-a] isoquinoline analog with bovine serum albumin
Authors: Ranade, Prasanna B
Navale, Dinesh N
Zote, Santosh W
Kulal, Dnyaneshwar K
Sheikh, Mohmad V
Ramana, M M V
Keywords: DCC;Cyclisation;Fluorescence;Circular dichroism;BSA
Issue Date: Aug-2021
Publisher: NIScPR-CSIR, India
Abstract: A condensation reaction between 1-cyclobutyl-3,4-dihydroisoquinoline and thioglycolic acid has been carried out using DCC yields 10b-cyclobutyl-5,6-dihydro-2H-thiazolo [2, 3-a] isoquinolin-3(10bH)-one [CBIQTGA]. The synthesized compound is characterised by using spectroscopic techniques. The interaction of CBIQTGA with bovine serum albumin has been studied using UV spectroscopy, spectrofluorimetry and circular dichroism techniques.
Page(s): 1081-1085
ISSN: 0975-0975(Online); 0376-4710(Print)
Appears in Collections:IJC-A Vol.60A(08) [August 2021]

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