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Title: Physicochemical characterization and HPTLC profiling of commercially available Kabasura Kudineer Chooranam
Authors: Shukla, Shatrunajay
Rehman, Mujeeb Ur
Tiwari, Ritu
Shukla, Mayank
Kalaiselvan, Vivekanandan
Kandadamy, Elavarasan
Prakash, Jai
Keywords: COVID-19;Guduchi;Kabasura Kudineer;Kalmegh;Lavang;Siddha medicine
Issue Date: Jul-2021
Publisher: NIScPR-CSIR, India
IPC Code: Int Cl.21: AK61K 36/00, A61K 36/19, A61K 36/59, A61K 36/67, A61K 36/185, A61K 38/19
Abstract: The novel coronavirus disease-2019 (COVID-19) is an ongoing viral infection and currently, limited vaccines with no post-market safety data or repurposed drugs are available to combat this contagious viral disease. Kabasura Kudineer, an official polyherbal Siddha medicine containing numerous herbal ingredients, is being practiced primarily in southern parts of India in the management of COVID-19 pandemic for boosting the respiratory system and treating fever with flu-like symptoms. The present study is carried out to scientifically validate the traditional claim and to confirm identity, quality and purity of marketed Kabasura Kudineer polyherbal formulations in India. Kabasura Kudineer Chooranam manufactured by two different manufacturers was procured from New Delhi, India. The physicochemical characterization of the samples was carried out in accordance with the standards laid down by Indian Pharmacopoeia (IP) 2018. HPTLC profiling of key ingredients including Kalmegh (Andrographis paniculata), Guduchi (Tinospora cordifolia), Pippali (Piper longum), Vasaka (Adhatoda vasica) and Lavang (Syzygium aromaticum) were also carried out in accordance with IP 2018 monographs. The chromatographic analysis showed the presence of all major ingredients in both the marketed preparations and all the physicochemical properties were also found comparable among preparations. Our findings may enhance the global acceptance of Siddha medicines practiced widely in India and also used for laying down the pharmacopoeial standards of Kabasura Kudineer Chooranam.
Page(s): 629-637
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.20(3) [July 2021]

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