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dc.contributor.authorAsma, Boukhennoufa-
dc.contributor.authorBoumediene, Meddah-
dc.contributor.authorAicha, Tir Touil Meddah-
dc.identifier.issn0976-0512 (Online); 0976-0504 (Print)-
dc.description.abstractMedicinal plants constitute a huge reserve of many therapeutic virtues recognized by their powerful effects since the dawn of time. Our research focused on the study of acute skin toxicity (AST) of Artemisia herba-alba Asso (Aha) essential oils, obtained by hydrodistillation. AST has been evaluated, using rats of the species Rattus norvegicus with reference to a method proposed by the organisation for economic co-operation and development (OECD) guideline. Biochemical parameters, alanine aminotransferase, aspartate aminotransférase, total bilirubin, direct bilirubin, and creatinine were measured in whole blood after animal sacrifices. In parallel, the histological liver and kidney sections were analyzed. The Lethal dose50 (LD50) value was found greater than 5000 mg/kg. In addition, the biochemical markers of the tested rats did not change during the experiment compared to the control group. No tissue damage has been detected. A. herba alba Asso essential oil was considered non-dangerous, which can be used to heal against all benign or severe illnesses.en_US
dc.publisherNIScPR-CSIR, Indiaen_US
dc.relation.ispartofseriesInt. cl. (2015.01)- A61K 36/00, A61K 36/28en_US
dc.sourceIJNPR Vol.12(2) [June 2021]en_US
dc.subjectAcute skin toxicityen_US
dc.subjectArtemisia herba-alba Assoen_US
dc.subjectEssential oilsen_US
dc.titleA study of acute dermal toxicity of Artemisia herba-alba Asso essential oilsen_US
Appears in Collections:IJNPR Vol.12(2) [June 2021]

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