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Title: Antibacterial potential of three naked-seeded (Gymnosperm) plants
Authors: Bissa, Sharad
Bohra, Avinash
Bohra, A
Keywords: Antibacterial
<i>Pinus</i><i> roxburghii</i>
<i>Cycas circinalis</i>
<i>Thuja orientalis</i>
Issue Date: Oct-2008
Publisher: CSIR
Series/Report no.: <b style="">Int. cl.<sup>8</sup>-</b>A61K 36/00, A61K 36/13, A61P 31/04
Abstract: The aerial parts of three gymnosperms, <b style=""><i>Pinus</i></b><b style=""><i> roxburghii </i>Sarg.</b><i> </i>(bark, needles and female cones)<i>, <b style="">Cycas</b><b style=""> circinalis </b></i><b style="">Linn. </b>(stem and leaves)<i> </i>and<i> <b style="">Thuja</b><b style=""> orientalis </b></i><b style="">Linn<i>.</i></b><i> </i>(stem and leaves)<i> </i>were extracted by Soxhlet apparatus using petroleum ether, ethanol, chloroform and water as solvent. The extracts were subjected to preliminary phytochemical screening and tested against four human pathogenic bacteria (<i style="">Escherichia coli, Salmonella typhi, Klebsiella pneumoniae </i>and<i style=""> Enterobacter aerogenes</i>) and one plant pathogenic bacteria, <i style="">Agrobacterium</i><i style=""> tumefaciens </i>by disc diffusion method. Among these extracts, the petroleum ether was found to be most effective in all the three plants. Maximum inhibition (20 mm) was recorded for needles extract of <b style=""><i>P. roxburghii</i></b><i> </i>against<i> Klebsiella pneumoniae</i>. The study suggests that these plants are promising phytomedicine for antibacterial activity.
Description: 420-425
ISSN: 0975-1092 (Online); 0972-592X (Print)
Appears in Collections:NPR Vol.7(5) [September-October 2008]

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