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NPR Vol.7(5) [September-October 2008] >


Title: Antibacterial potential of three naked-seeded (Gymnosperm) plants
Authors: Bissa, Sharad
Bohra, Avinash
Bohra, A
Keywords: Antibacterial
Pinus roxburghii
Cycas circinalis
Thuja orientalis
Issue Date: Oct-2008
Publisher: CSIR
IPC CodeInt. cl.8-A61K 36/00, A61K 36/13, A61P 31/04
Abstract: The aerial parts of three gymnosperms, Pinus roxburghii Sarg. (bark, needles and female cones), Cycas circinalis Linn. (stem and leaves) and Thuja orientalis Linn. (stem and leaves) were extracted by Soxhlet apparatus using petroleum ether, ethanol, chloroform and water as solvent. The extracts were subjected to preliminary phytochemical screening and tested against four human pathogenic bacteria (Escherichia coli, Salmonella typhi, Klebsiella pneumoniae and Enterobacter aerogenes) and one plant pathogenic bacteria, Agrobacterium tumefaciens by disc diffusion method. Among these extracts, the petroleum ether was found to be most effective in all the three plants. Maximum inhibition (20 mm) was recorded for needles extract of P. roxburghii against Klebsiella pneumoniae. The study suggests that these plants are promising phytomedicine for antibacterial activity.
Page(s): 420-425
ISSN: 0975-1092 (Online); 0972-592X (Print)
Source:NPR Vol.7(5) [September-October 2008]

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