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|Title:||Tea tree and jojoba oils enriched bigel loaded with isotretinoin for effective management of acne|
Saraf, Shubhini A.
|Keywords:||Acne;Bigel;Jojoba oil;Tea tree oil|
|IPC Code:||Int. cl. (2015.01)- A61K 9/00, A61K 36/00, A61P 17/10|
|Abstract:||The study is aimed at the preparation of isotretinoin (ITR) loaded bigel for acne therapy. Bigels were enriched with tea tree and jojoba oils known to bestowed soothing properties. Bigels were evaluated for the physiochemical parameters viz. pH, viscosity, etc, in vitro release, and ex vivo permeation. The results displayed enhanced retention and antimicrobial potential of optimized B2 gel when compared with plain gel and other formulations. Thus the bigel of isotretinoin could be a promising delivery system for the treatment of acne.|
|ISSN:||0976-0512 (Online); 0976-0504 (Print)|
|Appears in Collections:||IJNPR Vol.12(1) [March 2021]|
Files in This Item:
|IJNPR 12(1) 158-163.pdf||Main Article||367.77 kB||Adobe PDF||View/Open|
|IJNPR 12(1) 158-163_Suppl Data.pdf||Supplementary Data||1.38 MB||Adobe PDF||View/Open|
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