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Title: Evaluation of antioxidant properties of <i style="">Canthium</i><i style=""> parviflorum</i> Lam. leaves
Authors: Kumar, T Sathish
Shanmugam, S
Palvannan, T
Kumar, V M Bharathi
Keywords: Antioxidant property
Free radical scavenging activity
Total phenolic content
<i style="">Canthium</i><i style=""> parviflorum</i>
Issue Date: Apr-2008
Publisher: CSIR
Series/Report no.: <b>Int. cl.<sup>8</sup>—</b><b></b> A61K 36/00, A61K 36/74, A61K 127/00, A61P 17/18
Abstract: Ethanolic extract of <b><i style="">Canthium</i></b><b><i style=""> parviflorum</i></b> <b>Lam.</b> leaves was analyzed for their total antioxidant capacity, reducing power, metal chelating, ABTS<sup>+</sup> [2, 2-azinobis-3-ethylbenzothiazoline-6-sulphonate] radical scavenging and hydroxyl radical scavenging activities. The extract at 500 <img src='/image/spc_char/micro.gif'>g/ml showed maximum scavenging activity (51.60%) of ABTS radical cation followed by the iron chelation (45.12%) at the same concentration. However, the extract showed only moderate hydroxyl radical scavenging activity (6.42%). Total antioxidant capacity was found to be 12.9 mg ascorbic acid equivalents at 500 <img src='/image/spc_char/micro.gif'>g/ml extract concentration. There was a positive correlation between the total phenolic content and antioxidant capacity, R<sup>2</sup> = 0.8313, whereas the correlation between the total flavonoids and antioxidant capacity was determined to be R<sup>2</sup> = 0.8102. The results suggest that phenolics and flavonoids in the leaves provide considerable antioxidant activity.
Description: 122-126
ISSN: 0975-1092 (Online); 0972-592X (Print)
Appears in Collections:NPR Vol.7(2) [March-April 2008]

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