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Title: Evaluation of antioxidant properties of Canthium parviflorum Lam. leaves
Authors: Kumar, T Sathish
Shanmugam, S
Palvannan, T
Kumar, V M Bharathi
Keywords: Antioxidant property;Free radical scavenging activity;Total phenolic content;Flavonoids;Canthium parviflorum
Issue Date: Apr-2008
Publisher: CSIR
IPC Code: Int. cl.8 A61K 36/00, A61K 36/74, A61K 127/00, A61P 17/18
Abstract: Ethanolic extract of Canthium parviflorum Lam. leaves was analyzed for their total antioxidant capacity, reducing power, metal chelating, ABTS+ [2, 2-azinobis-3-ethylbenzothiazoline-6-sulphonate] radical scavenging and hydroxyl radical scavenging activities. The extract at 500 g/ml showed maximum scavenging activity (51.60%) of ABTS radical cation followed by the iron chelation (45.12%) at the same concentration. However, the extract showed only moderate hydroxyl radical scavenging activity (6.42%). Total antioxidant capacity was found to be 12.9 mg ascorbic acid equivalents at 500 g/ml extract concentration. There was a positive correlation between the total phenolic content and antioxidant capacity, R2 = 0.8313, whereas the correlation between the total flavonoids and antioxidant capacity was determined to be R2 = 0.8102. The results suggest that phenolics and flavonoids in the leaves provide considerable antioxidant activity.
Page(s): 122-126
ISSN: 0975-1092 (Online); 0972-592X (Print)
Appears in Collections:NPR Vol.7(2) [March-April 2008]

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