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Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)]
NPR Vol.7 [2008] >
NPR Vol.7(1) [January-February 2008] >

Title: Antibacterial activity of solvent fractions of crude water decoction of apical twigs and latex of Calotropis procera (Ait.) R. Br
Authors: Parabia, Farzin M
Kothari, I L
Parabia, M H
Keywords: Traditional wound healer
Calotropis procera
Antibacterial activity
Gram positive bacteria
Gram negative bacteria
crude water decoction
Issue Date: Feb-2008
Publisher: CSIR
IPC CodeInt. cl.8 A61K 36/00, A61P 31/04
Abstract: Water decoction of Calotropis procera (Ait.) R.Br. is reported as a purulent wound healer in Indian System of Medicine —Ayurveda. Antibacterial activity of solvent fractions derived from the crude water decoction of C. procera against pathogenic and non-pathogenic bacterial strains has been evaluated. Dried apical twigs and latex of the plant were used for getting extracts. Four solvent fractions of both the samples were tested for their antibacterial activity on eight opportunistic bacterial strains, viz. Staphylococcus aureus, S. epidermidis, Bacillus cereus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Serratia marcescens, Enterobacter aerogenes and Escherichia coli. Other pathogenic strains selected were Salmonella paratyphi A and S. typhi, and non-pathogenic strains were Bacillus subtilis and Micrococcus luteus. The disk diffusion method was used to determine the inhibitory effect of all the fractions of both the plant samples on twelve tested bacterial strains. Comparison of the inhibitory activity with already established eight antibiotics was carried out. The fractions of apical twigs of plant produced wider inhibition zones than the fractions of latex. The fractions of both the plant samples produced greatest inhibitory zone on Staphylococcus aureus one of the major wound infectious bacterial strain.
Page(s): 30-34
ISSN: 0975-1092 (Online); 0972-592X (Print)
Source:NPR Vol.7(1) [January-February 2008]

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