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Title: In vitro antifungal activity of Cassia alata Linn. flower extract
Authors: Abubacker, M N
Ramanathan, R
Kumar, T Senthil
Keywords: Antifungal activity;Cassia alata;Aflatoxin;Ringworm Senna;Plant pathogenic fungi;Human pathogenic fungi
Issue Date: Feb-2008
Publisher: CSIR
IPC Code: Int. cl.8— A61K 36/00, A61K 36/482, A61P 31/10
Abstract: The aqueous flower extract of Cassia alata Linn. (Family-Caesalpiniaceae) was investigated for antifungal activity by agar diffusion method against three distinct groups of fungi, viz. aflatoxin producing fungi, Aspergillus flavus (NCBT 101) and A. parasiticus (NCBT 128); plant pathogenic fungi, Fusarium oxysporum ( NCBT 156 ) and Helminthosporium oryzae (NCBT 165); and human pathogenic fungi Candida albicans (NCBT 140) and Microsporum audouinni (NCBT 173). Total inhibition (100%) of growth was seen at 10 and 15 mg/ml concentrations for aflatoxin producing fungal strains. Whereas for plant and human pathogenic fungi total inhibition was at 15mg/ml concentration. The minimum inhibitory concentration (MIC) values of the extract varied from 5.75 to 8.00mg/ml for these fungi. Thus, aqueous flower extract of C. alata can be used as a potential antifungal agent for these three varied groups of fungi.
Page(s): 6-9
ISSN: 0975-1092 (Online); 0972-592X (Print)
Appears in Collections:NPR Vol.7(1) [January-February 2008]

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