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Title: <i>In vitro</i> antifungal activity of <i>Cassia alata</i> Linn. flower extract
Authors: Abubacker, M N
Ramanathan, R
Kumar, T Senthil
Keywords: Antifungal activity
<i>Cassia alata</i>
Ringworm Senna
Plant pathogenic fungi
Human pathogenic fungi
Issue Date: Feb-2008
Publisher: CSIR
Series/Report no.: Int. cl.<sup>8</sup>— A61K 36/00, A61K 36/482, A61P 31/10
Abstract: The aqueous flower extract of <b><i>Cassia alata</i> Linn.</b> (Family-Caesalpiniaceae) was investigated for antifungal activity by agar diffusion method against three distinct groups of fungi, viz. aflatoxin producing fungi, <i>Aspergillus flavus</i> (NCBT 101) and <i>A. parasiticus</i> (NCBT 128); plant pathogenic fungi, <i>Fusarium oxysporum</i> ( NCBT 156 ) and Helminthosporium oryzae (NCBT 165); and human pathogenic fungi <i>Candida albicans</i> (NCBT 140) and <i>Microsporum audouinni </i>(NCBT 173). Total inhibition (100%) of growth was seen at 10 and 15 mg/ml concentrations for aflatoxin producing fungal strains. Whereas for plant and human pathogenic fungi total inhibition was at 15mg/ml concentration. The minimum inhibitory concentration (MIC) values of the extract varied from 5.75 to 8.00mg/ml for these fungi. Thus, aqueous flower extract of <b><i>C. alata</i></b> can be used as a potential antifungal agent for these three varied groups of fungi.
Description: 6-9
ISSN: 0975-1092 (Online); 0972-592X (Print)
Appears in Collections:NPR Vol.7(1) [January-February 2008]

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