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Title: Twinning in Marwari and Bharat Merino ewes and its relationship with Booroola <i style="">FecB</i> mutation
Authors: Kumar, S
Kolte, Atul P
Singh, V K
Keywords: <i style="">FecB </i>mutation
Issue Date: Oct-2006
Publisher: CSIR
Series/Report no.: Int. Cl.<sup>8</sup> C12N15/01
Abstract: The Booroola fecundity (<i style="">FecB</i>) is a single autosomal gene, which increases ovulation rate and litter size in sheep. High prolificacy in Garole and Booroola Merino sheep is due to a mutation in <i style="">FecB</i> gene, and by its virtue they produce twin or more lambs. The <i style="">FecB </i>genotyping was carried out by Forced RFLP-PCR technique in prolific Garole, non-prolific Marwari and Bharat Merino ewes with the aim to confirm linkage of twinning with <i style="">FecB</i> mutation. Garole ewes were selected which had at least one record of twins, triplets or more lambs. Marwari and Bharat Merino ewes were selected into two groups, one group had at least one record of twin and other group had only single lamb. Results showed that <i style="">FecB</i> mutation was associated with twinning/high litter size in Garole ewes, while all Marwari and Bharat Merino ewes were found non-carriers (<i style="">FecB</i><sup>++</sup>) for <i style="">FecB </i>mutation. The present study indicates that twinning in Marwari and Bharat Merino ewes is not linked with <i style="">FecB</i> mutation, and it may be due to various other extrinsic reasons, including environmental factors or other unknown genes.
Description: 482-485
ISSN: 0975-0967 (Online); 0972-5849 (Print)
Appears in Collections:IJBT Vol.05(4) [October 2006]

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