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dc.contributor.authorSaha, Subrata Kumar-
dc.contributor.authorSaha, Swadhin Kumar-
dc.contributor.authorDhara, Koushik-
dc.contributor.authorChattopadhyay, Pabitra-
dc.contributor.authorSarkar, Arnab-
dc.identifier.issn0975-0975(Online); 0376-4710(Print)-
dc.description.abstractAllyl triphenylphosphonium bromide based mito-tracker capped silicon quantum dot (Mito-SiQDs) has been synthesized through an inverse micelle process. It was then fully characterized by transmission electron microscopy, energy-dispersive X-ray spectroscopy, dynamic light scattering techniques and X-ray photoelectron spectroscopic method. Energy dispersive X-ray spectroscopy analyses of the quantum dots confirm the presence of carbon, silicon, phosphorous and bromine atoms in Mito-SiQDs. Morphological study by transmission electron microscopy experiment showed the formation of the particles of size 11-12 nm of quantum dot dimension. The high negative zeta potential value of –23.7 mV calculated from dynamic light scattering study indicates the high stability of the circumvent agglomeration of Mito-SiQDs. The mito-tracker capped silicon quantum dot has blue emission at 400 nm wavelength upon excitation at 327 nm. Mito-SiQDs has not shown any significant cytotoxic effect with 10 to 50 μL/mL concentration on HeLa cell line for at least up to 12 h of its treatment. The Mito-SiQDs would be useful a possible fluorescent marker to visualize mitochondrial subcellular compartment in living cell through fluorescence imaging study.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-A Vol.60A(01) [January 2021]en_US
dc.subjectSilicon quantum dotsen_US
dc.subjectMitochondrial targeten_US
dc.titleSynthesis and characterization of a new water-soluble non-cytotoxic mito-tracker capped silicon quantum doten_US
Appears in Collections:IJC-A Vol.60A(01) [January 2021]

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