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dc.contributor.authorNasr, I Al-
dc.identifier.issn0975-1068 (Online); 0972-5938 (Print)-
dc.description.abstractToxoplasmosis is a protozoal parasitic infection with serious consequences for immunocompromised people. The commercial pharmaceuticals used for treatment cause adverse effects and cannot provide a 100% cure. We investigated on antitoxoplasmal activities of eleven medicinal plants from seven different families used in the Al Qassim region of Saudi Arabia against infectious diseases. The plants were extracted in methanol. The methanolic extracts were evaluated against Toxoplasma gondii and the Vero cell line using the MTT assay. The results obtained revealed the maximum inhibitory effects of extracts of Citrullus colocynthis, Blepharis ciliaris and Aerva javanica with IC50 values of 27.7, 65.2 and 78 µg/ml, respectively against the parasite. However, at the effective levels of antitoxoplasmal activity extracts, of all the above plant species showed different degrees of cytotoxicity against the Vero cell line with SI values of 1.3, 0.8 and 1.1. Hence, we suggest further studies to isolate the active ingredients are highly recommended.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.relation.ispartofseriesInt. Cl.20: A61K 36/00en_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJTK Vol.19(4) [October 2020]en_US
dc.subjectAl Qassimen_US
dc.subjectin vitroen_US
dc.subjectMedicinal plantsen_US
dc.subjectSaudi Arabiaen_US
dc.titleEvaluation of in vitro antitoxoplasmal activity of some medicinal plants collected from Al Qassim, Saudi Arabiaen_US
Appears in Collections:IJTK Vol.19(4) [October 2020]

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