Please use this identifier to cite or link to this item:
Title: New insights on the antifungal activity of essential oil of Salvia desoleana Atzei et Picci, an endemic plant from folk medicine of Sardinia, Italy
Authors: Maxia, A
Piras, A
Falconieri, D
Maccioni, D
Porcedda, S
Gonçalves, M J
Cavaleiro, C
Salgueiro, L
Keywords: Antifungal activity;Ethnomedicine;Essential oil;Germ tube;Salvia desoleana
Issue Date: Oct-2020
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl.20: C23C 18/30,  A61K 36/00, C11B 9/00, F24H 3/08, A01N 1/00
Abstract: This work reports the results concerning the antifungal activity of the essential oil obtained from Salvia desoleana, an endemic plant from folk medicine of Sardinia Island, Italy. Chemical analysis of S. desoleana essential oil isolated by hydrodistillation was carried out by gas chromatography (GC-FID) and gas chromatography–mass spectrometry (GC-MS). The essential oil contains high amounts of oxygenated monoterpenes and sesquiterpene hydrocarbons, being linalyl acetate (21.0%), a-terpinyl acetate (17.3%), 1,8-cineole (6.7%), linalool (3.6%), sclareol (3.5%) and germacrene D (22.1%) the main compounds. The oil was more active against the yeast Cryptococcus neoformans and the dermatophyte Trichophyton rubrum with MIC values of 0.16 μL/mL and 0.32 μL/mL, respectively. The oil revealed an important inhibitory effect on the germ tube formation in C. albicans. It was able to achieve about 40% of inhibition of filamentation at concentrations as low as 0.08 µL/mL. These findings add significant information to the biological activity of the essential oil of S. desoleana, specifically to its antifungal properties, thus justifying and reinforcing the use of this plant in traditional medicine.
Page(s): 757-760
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.19(4) [October 2020]

Files in This Item:
File Description SizeFormat 
IJTK 19(4) 757-760.pdf403.37 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.