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Title: 3,6-Di(pyridin-2-yl)-1,2,4,5-s-tetrazine capped-gold nanoparticles as an efficient antibacterialagent against gram-positive Bacillus subtilis
Authors: Joardar, Sutapa
Ray, Shounak
Keywords: Antibacterial activity;Antibacterial mechanism;Gold nanoparticles;TEM analysis
Issue Date: Nov-2020
Publisher: NISCAIR-CSIR, India
Abstract: In current work, we present 3,6-di(pyridin-2-yl)-1,2,4,5-s-tetrazine (pytz) capped gold nanoparticles (TzAuNPs) as an potent antibacterial agent against Gram-positive bacteria. The antibacterial properties of TzAuNPs have been studied using Gram-positive Bacillus subtilis (ATCC 11774) by the plate count method and TzAuNPs is found to be highly effective against the strain. Furthermore, TzAuNPs also show significantly better antimicrobial activity against the bacterial strain when compared to pytz. The effect of TzAuNPs on the bacterial cell wall is also investigated by TEM analysis. This new antimicrobial material could be promising in future for the treatment infectious diseases caused by Gram-positive bacteria.
Page(s): 1627-1631
ISSN: 0975-0975(Online); 0376-4710(Print)
Appears in Collections:IJC-A Vol.59A(11) [November 2020]

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