Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/55577
Title: Kidney damage in COVID-19 patients with or without chronic kidney disease: Analysis of clinical characteristics and related risk factors
Authors: Liu, Hong
Wang, Huanlan
Tu, Can
Mao, Dongdong
Hu, Yanglin
Zou, Rong
Min, Yonglong
Xiong, Fei
Su, Wen
Keywords: Acute kidney injury (AKI);Anemia;CKD;Hypersensitive C-reactive protein;Serum creatinine;Cardiac troponin I
Issue Date: Nov-2020
Publisher: NISCAIR-CSIR, India
Abstract: COVID-19 poses more risk to patients who already suffer from other diseases, particularly respiratory disorder. In this study, we analyzed the clinical characteristics and related risk factors during hospitalization of COVID-19 patients admitted with kidney damage. A total of 102 COVID-19 patients with kidney damage [irrespective of their chronic kidney disease (CKD) history] during hospitalization were included in this study. The patients were divided into a core group and a group who developed critical illness or death. Clinical data included age, gender, length of hospitalization, clinical manifestations, medical history, hypersensitive C-reactive protein (hs -CRP), high serum creatinine, low cardiac troponin I (cTnI), and hemoglobin. Univariate and multivariate logistic regression models were used to analyze the risk factors of patients' outcome. Among the outcomes, 75 patients (73.53%) were cured, 27 (26.47%) developed to critical illness or death, 20 (19.61%) of them died. A total of 36 (4.26%) out of 845 COVID-19 patients, developed acute kidney injury (AKI). Decreased oxygen saturation, elevated hs-CRP, elevated serum creatinine, elevated cTnI, and anemia were related factors for COVID-19 patients who developed to critical illness or death (P <0.05). Decreased oxygen saturation, elevated hs-CRP and anemia were not independent factors, but elevated serum creatinine and elevated cTnI were independent factors for COVID-19 patients who developed to critical illness or death (P <0.05). Among COVID-19 patients with or without CKD but with kidney damage during hospitalization, patients with elevated serum creatinine and elevated TnI, more likely to developed critical illness or death.
Page(s): 811-817
URI: http://nopr.niscair.res.in/handle/123456789/55577
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.58(11) [November 2020]

Files in This Item:
File Description SizeFormat 
IJEB 58(11) 811-817.pdf644.73 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.