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http://nopr.niscair.res.in/handle/123456789/55448| Title: | Enantioselective bioreduction of heptan-2-one and octan-2-one catalyzed by Daucus carota cells |
| Authors: | Chanysheva, Aliya R Zorin, Vladimir V |
| Keywords: | Daucus carota;Bioreduction;Exogenous reducing agents;(2S)-(+)-heptan-2-ol;(2S)-(+)-octan-2-ol |
| Issue Date: | Sep-2020 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Synthesis of enantiomerically pure (2S)-(+)-heptan-2-ol and (2S)-(+)-octan-2-ol by bioreduction of heptan-2-one and octan-2-one using Daucus carota cells has been studied. Optimization of bioreduction conditions has been carried out in the presence of various exogenous reducing agents (ethanol, isopropanol, glucose). Conditions allowing to obtain (2S)-(+)-heptan-2-ol with 91% yield and optical purity 98% ee and (2S)-(+)-octan-2-ol in 95% yield and > 99% ee have been found. |
| Page(s): | 1381-1383 |
| URI: | http://nopr.niscair.res.in/handle/123456789/55448 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.59B(09) [September 2020] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 59B(9) 1381-1383.pdf | Main Article | 137.87 kB | Adobe PDF | View/Open |
| IJCB 59B(9) 1381-1383_Suppl Data.pdf | Supplementary Data | 433.9 kB | Adobe PDF | View/Open |
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