Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/55448
Title: Enantioselective bioreduction of heptan-2-one and octan-2-one catalyzed by Daucus carota cells
Authors: Chanysheva, Aliya R
Zorin, Vladimir V
Keywords: Daucus carota;Bioreduction;Exogenous reducing agents;(2S)-(+)-heptan-2-ol;(2S)-(+)-octan-2-ol
Issue Date: Sep-2020
Publisher: NISCAIR-CSIR, India
Abstract: Synthesis of enantiomerically pure (2S)-(+)-heptan-2-ol and (2S)-(+)-octan-2-ol by bioreduction of heptan-2-one and octan-2-one using Daucus carota cells has been studied. Optimization of bioreduction conditions has been carried out in the presence of various exogenous reducing agents (ethanol, isopropanol, glucose). Conditions allowing to obtain (2S)-(+)-heptan-2-ol with 91% yield and optical purity 98% ee and (2S)-(+)-octan-2-ol in 95% yield and > 99% ee have been found.
Page(s): 1381-1383
URI: http://nopr.niscair.res.in/handle/123456789/55448
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.59B(09) [September 2020]

Files in This Item:
File Description SizeFormat 
IJCB 59B(9) 1381-1383.pdfMain Article137.87 kBAdobe PDFView/Open
IJCB 59B(9) 1381-1383_Suppl Data.pdfSupplementary Data433.9 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.