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Title: Potassium alum as a naturally mineral and economical catalyst for the one-pot, multi-component and clean synthesis of 2-oxo(thio)-1,2,3,4-tetrahydropyrimidines and N-aryl-3-aminodihydropyrrol-2-one-4-carboxylates
Authors: Mohamadpour, Farzaneh
Keywords: Potassium alum;2-Oxo(thio)-1,2,3,4-tetrahydropyrimidines;N-aryl-3-aminodihydropyrrol-2-one-4-carboxylate;Naturally mineral catalyst;Multi-component synthesis
Issue Date: Aug-2020
Publisher: NISCAIR-CSIR, India
Abstract: An environmental friendly synthetic route for potassium alum catalyzed one-pot multi-component synthesis of biologically active 2-oxo(thio)-1,2,3,4-tetrahydropyrimidines and N--aryl-3-aminodihydropyrrol-2-one-4-carboxylates has developed. The present synthetic route has the notable advantages of natural, mineral, inexpensive and non-toxic catalyst, mild reaction conditions, eco-friendly, one-pot and good to high yield of biological active products. This method is simple for work up and the compound formed filtered and purified just by simple crystallization.
Page(s): 1183-1190
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.59B(08) [August 2020]

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