Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSelvamani, S-
dc.contributor.authorDailin, D J-
dc.contributor.authorRostom, M-
dc.contributor.authorMalek, R A-
dc.contributor.authorGupta, V K-
dc.contributor.authorEl-Enshasy, H A-
dc.identifier.issn0975-1084 (Online); 0022-4456 (Print)-
dc.description.abstractProbiotics referred to a group of living microorganisms which highly influence the human health. A number of studies have highlighted on the bio-therapeutic potential of Lactobacillus reuteri strains, especially in treating eradication of Helicobacter pylori. Therefore, in present investigation, statistical methods were applied to optimize medium composition for high cell mass production of L. reuteri strain DSM 20016T. Most influencing medium components were screened by using Plackett-Burman and optimized using Box-Bhenken experimental design. The concentration of lactose, yeast extract and phosphate in cultivation medium has shown significant effect on the cell mass production. The highest cell mass obtained after 48h incubation was 3.96 ± 0.02 gL−1 in RSM-optimized medium compared to 1.76 ± 0.17 gL−1 in un-optimized medium.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceJSIR Vol.79(09) [September 2020]en_US
dc.subjectProbiotic cultivationen_US
dc.subjectHigh cell mass productionen_US
dc.subjectMedium optimizationen_US
dc.titleOptimizing Medium Components to Enhance High Cell Mass Production of Biotherapeutic Strain Lactobacillus reuteri DSM 20016T by Statistical Methoden_US
Appears in Collections:JSIR Vol.79(09) [September 2020]

Files in This Item:
File Description SizeFormat 
JSIR 79(9) 798-803.pdf409.5 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.